BDBM50119945 2-[1-(3-Methyl-benzyl)-piperidin-4-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::CHEMBL105011

SMILES: CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(C)c2)CC1

InChI Key: InChIKey=RYPURVOUHFFJCE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119945 (2-[1-(3-Methyl-benzyl)-piperidin-4-yl]-1-(2-methyl...) Show SMILES CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(C)c2)CC1 Show InChI InChI=1S/C24H30N2O/c1-18-6-5-7-21(14-18)17-25-12-10-20(11-13-25)16-24(27)26-19(2)15-22-8-3-4-9-23(22)26/h3-9,14,19-20H,10-13,15-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards human dopamine D4 receptor was determined via standard competitive displacement assays using [3H]-YM 09151 as radioligand				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50119945 (2-[1-(3-Methyl-benzyl)-piperidin-4-yl]-1-(2-methyl...) Show SMILES CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(C)c2)CC1 Show InChI InChI=1S/C24H30N2O/c1-18-6-5-7-21(14-18)17-25-12-10-20(11-13-25)16-24(27)26-19(2)15-22-8-3-4-9-23(22)26/h3-9,14,19-20H,10-13,15-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards Alpha-1 adrenergic receptor via standard competitive displacement assay using rat brain homogenate with [3H]prazosin as radi...				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119945 (2-[1-(3-Methyl-benzyl)-piperidin-4-yl]-1-(2-methyl...) Show SMILES CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(C)c2)CC1 Show InChI InChI=1S/C24H30N2O/c1-18-6-5-7-21(14-18)17-25-12-10-20(11-13-25)16-24(27)26-19(2)15-22-8-3-4-9-23(22)26/h3-9,14,19-20H,10-13,15-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards human dopamine D2 receptor, using [3H]-YM-09151 as a radioligand				Bioorg Med Chem Lett 12: 3105-9 (2002) BindingDB Entry DOI: 10.7270/Q2JM2908
					More data for this Ligand-Target Pair