BDBM50119986 (S)-1-{2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-acetyl}-2,3-dihydro-1H-indole-2-carboxylic acid methyl ester::CHEMBL105745

SMILES: COC(=O)[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1

InChI Key: InChIKey=UXFGATIIHSOJJZ-QFIPXVFZSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119986 ((S)-1-{2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-acet...) Show SMILES COC(=O)[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 Show InChI InChI=1S/C24H29N3O3/c1-18-7-9-19(10-8-18)16-25-11-13-26(14-12-25)17-23(28)27-21-6-4-3-5-20(21)15-22(27)24(29)30-2/h3-10,22H,11-17H2,1-2H3/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards Dopamine type 4 receptor was determined by competitive displacement assays using [3H]-YM 09151 as the competitive ligand				Bioorg Med Chem Lett 12: 3111-5 (2002) BindingDB Entry DOI: 10.7270/Q2DZ07ND
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119986 ((S)-1-{2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-acet...) Show SMILES COC(=O)[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 Show InChI InChI=1S/C24H29N3O3/c1-18-7-9-19(10-8-18)16-25-11-13-26(14-12-25)17-23(28)27-21-6-4-3-5-20(21)15-22(27)24(29)30-2/h3-10,22H,11-17H2,1-2H3/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	491	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards Dopamine type 2 receptor was determined by displacement assays using [3H]-YM 09151 as the competitive ligand				Bioorg Med Chem Lett 12: 3111-5 (2002) BindingDB Entry DOI: 10.7270/Q2DZ07ND
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50119986 ((S)-1-{2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-acet...) Show SMILES COC(=O)[C@@H]1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(C)cc2)CC1 Show InChI InChI=1S/C24H29N3O3/c1-18-7-9-19(10-8-18)16-25-11-13-26(14-12-25)17-23(28)27-21-6-4-3-5-20(21)15-22(27)24(29)30-2/h3-10,22H,11-17H2,1-2H3/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity towards Alpha-1 adrenergic receptor was determined by competitive displacement assays using rat brain homogenate with [3H]prazosin a...				Bioorg Med Chem Lett 12: 3111-5 (2002) BindingDB Entry DOI: 10.7270/Q2DZ07ND
					More data for this Ligand-Target Pair