BDBM50120139 C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-propyl)-azetidin-2-yl]}-methylamine::CHEMBL320804

SMILES: CCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1

InChI Key: InChIKey=SJIMHAZVVWCGGD-JLMCIHFGSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50120139 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-prop...) Show SMILES CCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C19H23ClN2/c1-2-17(14-7-4-3-5-8-14)22-12-11-18(22)19(21)15-9-6-10-16(20)13-15/h3-10,13,17-19H,2,11-12,21H2,1H3/t17?,18-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120139 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-prop...) Show SMILES CCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C19H23ClN2/c1-2-17(14-7-4-3-5-8-14)22-12-11-18(22)19(21)15-9-6-10-16(20)13-15/h3-10,13,17-19H,2,11-12,21H2,1H3/t17?,18-,19+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120139 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-prop...) Show SMILES CCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C19H23ClN2/c1-2-17(14-7-4-3-5-8-14)22-12-11-18(22)19(21)15-9-6-10-16(20)13-15/h3-10,13,17-19H,2,11-12,21H2,1H3/t17?,18-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120139 (C-{(R)-C-(3-Chloro-phenyl)-C-[(S)-1-(1-phenyl-prop...) Show SMILES CCC(N1CC[C@H]1[C@H](N)c1cccc(Cl)c1)c1ccccc1 Show InChI InChI=1S/C19H23ClN2/c1-2-17(14-7-4-3-5-8-14)22-12-11-18(22)19(21)15-9-6-10-16(20)13-15/h3-10,13,17-19H,2,11-12,21H2,1H3/t17?,18-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor delta 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair