BDBM50120169 C-[(R)-C-{(S)-1-[Bis-(3-trifluoromethyl-phenyl)-methyl]-azetidin-2-yl}-C-(3-chloro-phenyl)]-methylamine::CHEMBL320061

SMILES: N[C@@H]([C@@H]1CCN1C(c1cccc(c1)C(F)(F)F)c1cccc(c1)C(F)(F)F)c1cccc(Cl)c1

InChI Key: InChIKey=MZJLFDPTAQVJLX-FCHUYYIVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50120169 (C-[(R)-C-{(S)-1-[Bis-(3-trifluoromethyl-phenyl)-me...) Show SMILES N[C@@H]([C@@H]1CCN1C(c1cccc(c1)C(F)(F)F)c1cccc(c1)C(F)(F)F)c1cccc(Cl)c1 Show InChI InChI=1S/C25H21ClF6N2/c26-20-9-3-4-15(14-20)22(33)21-10-11-34(21)23(16-5-1-7-18(12-16)24(27,28)29)17-6-2-8-19(13-17)25(30,31)32/h1-9,12-14,21-23H,10-11,33H2/t21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair