BDBM50120334 CHEMBL3616682

SMILES: CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2ccc(Cl)c(F)c2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=WDPNNRCZWVGLPU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50120334 (CHEMBL3616682) Show SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2ccc(Cl)c(F)c2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C32H24ClF4N3O4/c1-18(19-2-4-21(5-3-19)31(43)38-15-14-29(41)42)40-28-17-22(20-6-10-24(11-7-20)44-32(35,36)37)8-12-25(28)30(39-40)23-9-13-26(33)27(34)16-23/h2-13,16-18H,14-15H2,1H3,(H,38,43)(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120334 (CHEMBL3616682) Show SMILES CC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2ccc(Cl)c(F)c2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C32H24ClF4N3O4/c1-18(19-2-4-21(5-3-19)31(43)38-15-14-29(41)42)40-28-17-22(20-6-10-24(11-7-20)44-32(35,36)37)8-12-25(28)30(39-40)23-9-13-26(33)27(34)16-23/h2-13,16-18H,14-15H2,1H3,(H,38,43)(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair