BDBM50120343 3-[(S)-8-Chloro-6-(2-fluoro-phenyl)-2-methyl-4H-3,5,10b-triaza-benzo[e]azulen-4-yl]-propionic acid methyl ester::CHEMBL320277
SMILES: COC(=O)CC[C@@H]1N=C(c2ccccc2F)c2cc(Cl)ccc2-n2cc(C)nc12
InChI Key: InChIKey=BRGDLUDFNXOQJE-SFHVURJKSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat)) | BDBM50120343 (3-[(S)-8-Chloro-6-(2-fluoro-phenyl)-2-methyl-4H-3,...) | PDB KEGG GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity of the compound was determined against rat benzodiazepine (BZD) receptor | Bioorg Med Chem Lett 12: 3219-22 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6X4F | |||||||||||
More data for this Ligand-Target Pair |