null

SMILES: CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)cc1Cl

InChI Key: InChIKey=WDPJGUOYBLRNMQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50120363 (CHEMBL3616691) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)cc1Cl Show InChI InChI=1S/C37H35ClF3N3O5/c1-4-5-6-31(22-7-9-23(10-8-22)36(47)42-18-17-34(45)46)44-32-19-24(27-15-13-26(48-2)21-30(27)38)11-14-28(32)35(43-44)29-20-25(37(39,40)41)12-16-33(29)49-3/h7-16,19-21,31H,4-6,17-18H2,1-3H3,(H,42,47)(H,45,46)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120363 (CHEMBL3616691) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1ccc(OC)cc1Cl Show InChI InChI=1S/C37H35ClF3N3O5/c1-4-5-6-31(22-7-9-23(10-8-22)36(47)42-18-17-34(45)46)44-32-19-24(27-15-13-26(48-2)21-30(27)38)11-14-28(32)35(43-44)29-20-25(37(39,40)41)12-16-33(29)49-3/h7-16,19-21,31H,4-6,17-18H2,1-3H3,(H,42,47)(H,45,46)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair