BDBM50120537 8-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-imidazo[1,2-a]pyridine::CHEMBL72022
SMILES: Cc1cccn2cc(nc12)-c1ccc(OCCCN2CCCCC2)cc1
InChI Key: InChIKey=IUKYHUQESODSDZ-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50120537 (8-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Antagonist activity for human histamine H3 receptor was determined | Bioorg Med Chem Lett 12: 3309-12 (2002) BindingDB Entry DOI: 10.7270/Q2KH0MPG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50120537 (8-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Binding affinity for human histamine H3 receptor | Bioorg Med Chem Lett 12: 3309-12 (2002) BindingDB Entry DOI: 10.7270/Q2KH0MPG | |||||||||||
More data for this Ligand-Target Pair |