BDBM50120607 CHEMBL3618289
SMILES: CN(C)c1ccc(cc1)C1N2C(Sc3ccccc23)=NC(C)=C1C(C)=O
InChI Key: InChIKey=WCPCRCAWSDQORR-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Myosin light chain kinase, smooth muscle (Homo sapiens (Human)) | BDBM50120607 (CHEMBL3618289) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.37E+10 | n/a | n/a | n/a | n/a | n/a | n/a |
Rashtrasant Tukadoji Maharaj Nagpur University Curated by ChEMBL | Assay Description Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting method | Bioorg Med Chem 23: 6689-713 (2015) BindingDB Entry DOI: 10.7270/Q2P55Q95 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myosin light chain kinase, smooth muscle (Homo sapiens (Human)) | BDBM50120607 (CHEMBL3618289) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rashtrasant Tukadoji Maharaj Nagpur University Curated by ChEMBL | Assay Description Inhibition of MLCK (unknown origin) incubated for 15 mins using [gamma-32P]-ATP by scintillation counting method | Bioorg Med Chem 23: 6689-713 (2015) BindingDB Entry DOI: 10.7270/Q2P55Q95 | |||||||||||
More data for this Ligand-Target Pair |