BDBM50120694 CHEMBL356975::N-Hydroxy-2-(3-methyl-2-oxo-3-phenyl-pyrrolidin-1-yl)-propionamide

SMILES: C[C@@H](N1CC[C@](C)(C1=O)c1ccccc1)C(=O)NO

InChI Key: InChIKey=GDUSADXUOJTTQS-YGRLFVJLSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50120694 (CHEMBL356975 | N-Hydroxy-2-(3-methyl-2-oxo-3-pheny...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccccc1)C(=O)NO Show InChI InChI=1S/C14H18N2O3/c1-10(12(17)15-19)16-9-8-14(2,13(16)18)11-6-4-3-5-7-11/h3-7,10,19H,8-9H2,1-2H3,(H,15,17)/t10-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity for Matrix metalloprotease-2 (MMP-2)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50120694 (CHEMBL356975 | N-Hydroxy-2-(3-methyl-2-oxo-3-pheny...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccccc1)C(=O)NO Show InChI InChI=1S/C14H18N2O3/c1-10(12(17)15-19)16-9-8-14(2,13(16)18)11-6-4-3-5-7-11/h3-7,10,19H,8-9H2,1-2H3,(H,15,17)/t10-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	221	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity towards Matrix metalloprotease-1 (MMP-1)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50120694 (CHEMBL356975 | N-Hydroxy-2-(3-methyl-2-oxo-3-pheny...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccccc1)C(=O)NO Show InChI InChI=1S/C14H18N2O3/c1-10(12(17)15-19)16-9-8-14(2,13(16)18)11-6-4-3-5-7-11/h3-7,10,19H,8-9H2,1-2H3,(H,15,17)/t10-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity towards Matrix metalloprotease-9 (MMP-9)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig))	BDBM50120694 (CHEMBL356975 | N-Hydroxy-2-(3-methyl-2-oxo-3-pheny...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccccc1)C(=O)NO Show InChI InChI=1S/C14H18N2O3/c1-10(12(17)15-19)16-9-8-14(2,13(16)18)11-6-4-3-5-7-11/h3-7,10,19H,8-9H2,1-2H3,(H,15,17)/t10-,14+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity for Tumor necrosis factor alpha converting enzyme (TACE)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair