BDBM50120994 CHEMBL3621447
SMILES: [H][C@]12CN(c3nc(OC)c(NC(=O)CC(C)(C)C)c(OC)n3)[C@]([H])(CO1)C2
InChI Key: InChIKey=PDEHAXXTSJZZTG-QWRGUYRKSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human)) | BDBM50120994 (CHEMBL3621447) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.89E+3 | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Activation of human Kv7.2/7.3 expressed in CHOK1 cells | Bioorg Med Chem Lett 25: 4941-4 (2015) BindingDB Entry DOI: 10.7270/Q28054FG | |||||||||||
More data for this Ligand-Target Pair |