BDBM50120995 CHEMBL3621448

SMILES: COc1nc(nc(OC)c1NC(=O)CC(C)(C)C)N1CC2(COC2)C1

InChI Key: InChIKey=RCAHCEKSWSAUGK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human))	BDBM50120995 (CHEMBL3621448) Show SMILES COc1nc(nc(OC)c1NC(=O)CC(C)(C)C)N1CC2(COC2)C1 Show InChI InChI=1S/C17H26N4O4/c1-16(2,3)6-11(22)18-12-13(23-4)19-15(20-14(12)24-5)21-7-17(8-21)9-25-10-17/h6-10H2,1-5H3,(H,18,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	9.19E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human Kv7.2/7.3 expressed in CHOK1 cells				Bioorg Med Chem Lett 25: 4941-4 (2015) BindingDB Entry DOI: 10.7270/Q28054FG
					More data for this Ligand-Target Pair