BDBM50120997 CHEMBL3621795

SMILES: COC1CCN(CC1)c1nc(OC)c(NC(=O)CC2CCCCC2)c(OC)n1

InChI Key: InChIKey=LQEXJDNYURDVPL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human))	BDBM50120997 (CHEMBL3621795) Show SMILES COC1CCN(CC1)c1nc(OC)c(NC(=O)CC2CCCCC2)c(OC)n1 Show InChI InChI=1S/C20H32N4O4/c1-26-15-9-11-24(12-10-15)20-22-18(27-2)17(19(23-20)28-3)21-16(25)13-14-7-5-4-6-8-14/h14-15H,4-13H2,1-3H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	162	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human Kv7.2/7.3 expressed in CHOK1 cells				Bioorg Med Chem Lett 25: 4941-4 (2015) BindingDB Entry DOI: 10.7270/Q28054FG
					More data for this Ligand-Target Pair