BDBM50121292 2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfanyl-propionylamino]-5-guanidino-pentanoic acid {2-phenyl-1-[2-phenyl-1-(3-phenyl-propylcarbamoyl)-ethylcarbamoyl]-ethyl}-amide::CHEMBL148943

SMILES: CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCCc1ccccc1

InChI Key: InChIKey=RVZQSASJHSEWSL-ZXSKELPHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM50121292 (2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...) Show SMILES CSCC(NC(=O)Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C51H60N8O5S/c1-65-35-45(56-46(60)34-39-26-28-41(29-27-39)40-23-12-5-13-24-40)50(64)57-42(25-15-31-55-51(52)53)48(62)59-44(33-38-20-10-4-11-21-38)49(63)58-43(32-37-18-8-3-9-19-37)47(61)54-30-14-22-36-16-6-2-7-17-36/h2-13,16-21,23-24,26-29,42-45H,14-15,22,25,30-35H2,1H3,(H,54,61)(H,56,60)(H,57,64)(H,58,63)(H,59,62)(H4,52,53,55)/t42-,43?,44?,45?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council of Canada Curated by ChEMBL					Assay Description Inhibitory activity against human Cathepsin L				J Med Chem 45: 5321-9 (2002) BindingDB Entry DOI: 10.7270/Q23B5ZH6
					More data for this Ligand-Target Pair