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SMILES: CC(C)C[C@H](C[Si](O)(O)CNC(=O)CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C([O-])=O

InChI Key: InChIKey=WQWQCIBJEALKNR-UXHICEINSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121453   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thermolysin


(Bacillus thermoproteolyticus)		BDBM50121453
PNG
(CHEMBL334233 | Sodium; (S)-2-[(S)-2-({dihydroxy-[(...)
Show SMILES CC(C)C[C@H](C[Si](O)(O)CNC(=O)CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C([O-])=O
Show InChI InChI=1S/C23H38N2O6Si/c1-16(2)12-19(22(27)25-20(23(28)29)13-17(3)4)14-32(30,31)15-24-21(26)11-10-18-8-6-5-7-9-18/h5-9,16-17,19-20,30-31H,10-15H2,1-4H3,(H,24,26)(H,25,27)(H,28,29)/p-1/t19-,20+/m1/s1
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
PubMed
 41n/an/an/an/an/an/an/an/a



State University of New York

Curated by ChEMBL


Assay Description
Competitive inhibition of thermolysin evaluated using the substrate FAGLA (Sigma); Competitive binding observed

Bioorg Med Chem Lett 12: 3625-7 (2002)


BindingDB Entry DOI: 10.7270/Q269744P
More data for this
Ligand-Target Pair