BDBM50121606 4-{2-[4-(3-Phenyl-propylamino)-6-piperazin-1-yl-[1,3,5]triazin-2-ylamino]-ethyl}-phenol::CHEMBL150704
SMILES: Oc1ccc(CCNc2nc(NCCCc3ccccc3)nc(n2)N2CCNCC2)cc1
InChI Key: InChIKey=CHVWALVAKFEZLK-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50121606 (4-{2-[4-(3-Phenyl-propylamino)-6-piperazin-1-yl-[1...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligand | J Med Chem 45: 5492-505 (2002) BindingDB Entry DOI: 10.7270/Q2J965RW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50121606 (4-{2-[4-(3-Phenyl-propylamino)-6-piperazin-1-yl-[1...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description In vitro binding affinity towards human Estrogen receptor alpha using [3H]-17-beta-estradiol as radioligand | J Med Chem 45: 5492-505 (2002) BindingDB Entry DOI: 10.7270/Q2J965RW | |||||||||||
More data for this Ligand-Target Pair |