null
SMILES: Cc1cccc(C)c1OCC(=O)NN(Cc1ccccc1)C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cccc(O)c1C
InChI Key: InChIKey=ZLGGLFCORSRTDX-NYDCQLBNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50121728 (CHEMBL172012 | KNI-1279 | N-[(S)-3-{N-Benzyl-N'-[2...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Pharmaceutical University Curated by ChEMBL | Assay Description Inhibitory activity of the compound against HIV-1 protease | Bioorg Med Chem Lett 13: 93-6 (2002) BindingDB Entry DOI: 10.7270/Q2N29W9D | |||||||||||
More data for this Ligand-Target Pair |