BDBM50122078 CHEMBL422515::N-[1-[7-(4-Amino-butylamino)-heptylcarbamoyl]-2-(4-hydroxy-phenyl)-ethyl]-butyramide
SMILES: CCCC(=O)NC(Cc1ccc(O)cc1)C(=O)NCCCCCCCNCCCCN
InChI Key: InChIKey=YKCMCIWNASWOOP-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GRIA1 (Homo sapiens (Human)) | BDBM50122078 (CHEMBL422515 | N-[1-[7-(4-Amino-butylamino)-heptyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 168 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of the (-80 mV) current elicited by 100 microM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA. | J Med Chem 45: 5745-54 (2002) BindingDB Entry DOI: 10.7270/Q2BP025P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA1 (Homo sapiens (Human)) | BDBM50122078 (CHEMBL422515 | N-[1-[7-(4-Amino-butylamino)-heptyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of the (-40 mV) current elicited by 100 microM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA. | J Med Chem 45: 5745-54 (2002) BindingDB Entry DOI: 10.7270/Q2BP025P | |||||||||||
More data for this Ligand-Target Pair |