BDBM50122102 3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetramethyl-benzyl)-1H-indol-4-ylmethylene]-hydrazide::CHEMBL152640::N'-((1-(2,3,5,6-tetramethylbenzyl)-1H-indol-4-yl)methylene)-3-cyano-4-hydroxybenzohydrazide

SMILES: Cc1cc(C)c(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(c4)C#N)cccc23)c1C

InChI Key: InChIKey=HNTXQDRFWJBZGO-FJEPWZHXSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50122102 (3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetrame...) Show SMILES Cc1cc(C)c(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(c4)C#N)cccc23)c1C Show InChI InChI=1S/C28H26N4O2/c1-17-12-18(2)20(4)25(19(17)3)16-32-11-10-24-22(6-5-7-26(24)32)15-30-31-28(34)21-8-9-27(33)23(13-21)14-29/h5-13,15,33H,16H2,1-4H3,(H,31,34)/b30-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50122102 (3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetrame...) Show SMILES Cc1cc(C)c(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(c4)C#N)cccc23)c1C Show InChI InChI=1S/C28H26N4O2/c1-17-12-18(2)20(4)25(19(17)3)16-32-11-10-24-22(6-5-7-26(24)32)15-30-31-28(34)21-8-9-27(33)23(13-21)14-29/h5-13,15,33H,16H2,1-4H3,(H,31,34)/b30-15+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor				Bioorg Med Chem Lett 24: 4266-70 (2014) Article DOI: 10.1016/j.bmcl.2014.07.025 BindingDB Entry DOI: 10.7270/Q2ZW1NK4
					More data for this Ligand-Target Pair
Glucagon receptor (Rattus norvegicus)	BDBM50122102 (3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetrame...) Show SMILES Cc1cc(C)c(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(c4)C#N)cccc23)c1C Show InChI InChI=1S/C28H26N4O2/c1-17-12-18(2)20(4)25(19(17)3)16-32-11-10-24-22(6-5-7-26(24)32)15-30-31-28(34)21-8-9-27(33)23(13-21)14-29/h5-13,15,33H,16H2,1-4H3,(H,31,34)/b30-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro binding affinity of the compound towards rat glucagon receptor				J Med Chem 45: 5755-75 (2002) BindingDB Entry DOI: 10.7270/Q26W99FD
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50122102 (3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetrame...) Show SMILES Cc1cc(C)c(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(c4)C#N)cccc23)c1C Show InChI InChI=1S/C28H26N4O2/c1-17-12-18(2)20(4)25(19(17)3)16-32-11-10-24-22(6-5-7-26(24)32)15-30-31-28(34)21-8-9-27(33)23(13-21)14-29/h5-13,15,33H,16H2,1-4H3,(H,31,34)/b30-15+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cells				J Med Chem 45: 5755-75 (2002) BindingDB Entry DOI: 10.7270/Q26W99FD
					More data for this Ligand-Target Pair