BDBM50122352 (2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopropyl]-hexa-2,4-dienoic acid::CHEMBL89058

SMILES: C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O

InChI Key: InChIKey=QCNVQJSKAXKQEF-ZFKNLEDPSA-N

Data: 6 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50122352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-RA binding to human Retinoid X receptor RXR alpha				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Mus musculus)	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing mouse Retinoid X receptor RXR beta				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA binding to human Retinoic acid receptor RAR alpha				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair
Retinoid X receptor gamma (Mus musculus)	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expresing mouse Retinoid X receptor RXR gamma				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Mus musculus)	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expresing human Retinoic acid receptor RAR beta				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity against Retinoic acid receptor RAR beta in CV-1 cells				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA binding to human Retinoic acid receptor RAR gamma				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA binding to human Retinoic acid receptor RAR gamma				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50122352 ((2E,4E)-3-Methyl-6-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\CC1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34O2/c1-17(14-22(26)27)8-7-9-25(12-13-25)19-16-21-20(15-18(19)2)23(3,4)10-11-24(21,5)6/h7-8,14-16H,9-13H2,1-6H3,(H,26,27)/b8-7+,17-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-RA binding to human Retinoid X receptor RXR gamma				Bioorg Med Chem Lett 13: 261-4 (2002) BindingDB Entry DOI: 10.7270/Q29P310V
					More data for this Ligand-Target Pair