BDBM50122591 4,6-dichloro-3-[({[(phenylsulfonyl)amino]carbonyl}amino)methyl]-1H-indole-2-carboxylic acid::CHEMBL159739

SMILES: OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1CNC(=O)NS(=O)(=O)c1ccccc1

InChI Key: InChIKey=CISHLPQOGZOLEP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50122591 (4,6-dichloro-3-[({[(phenylsulfonyl)amino]carbonyl}...) Show SMILES OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1CNC(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H13Cl2N3O5S/c18-9-6-12(19)14-11(15(16(23)24)21-13(14)7-9)8-20-17(25)22-28(26,27)10-4-2-1-3-5-10/h1-7,21H,8H2,(H,23,24)(H2,20,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-Universität Curated by ChEMBL					Assay Description Tested for the affinity for the glycine binding site of the N-methyl-D-aspartate glutamate receptor using pig brain membranes in binding assay with [...				J Med Chem 46: 64-73 (2002) Article DOI: 10.1021/jm020955n BindingDB Entry DOI: 10.7270/Q2NZ8703
					More data for this Ligand-Target Pair