BDBM50122597 4,6-Dichloro-3-(5-isopropyl-2,4-dioxo-3-phenyl-imidazolidin-1-ylmethyl)-1H-indole-2-carboxylic acid::CHEMBL424524

SMILES: CC(C)c1c(O)n(-c2ccccc2)c(=O)n1Cc1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O

InChI Key: InChIKey=WNICGFXVDFQZHY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50122597 (4,6-Dichloro-3-(5-isopropyl-2,4-dioxo-3-phenyl-imi...) Show SMILES CC(C)c1c(O)n(-c2ccccc2)c(=O)n1Cc1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O Show InChI InChI=1S/C22H19Cl2N3O4/c1-11(2)19-20(28)27(13-6-4-3-5-7-13)22(31)26(19)10-14-17-15(24)8-12(23)9-16(17)25-18(14)21(29)30/h3-9,11,25,28H,10H2,1-2H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-Universität Curated by ChEMBL					Assay Description Tested for the affinity for the glycine binding site of the N-methyl-D-aspartate glutamate receptor using pig brain membranes in binding assay with [...				J Med Chem 46: 64-73 (2002) Article DOI: 10.1021/jm020955n BindingDB Entry DOI: 10.7270/Q2NZ8703
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