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BDBM50122600 4,6-Dichloro-3-[3-(4-chloro-phenyl)-2,4-dioxo-imidazolidin-1-ylmethyl]-1H-indole-2-carboxylic acid::CHEMBL163307

SMILES: OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1Cn1cc(O)n(-c2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=PIRGRUCXTLOGHL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122600   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))
BDBM50122600
PNG
(4,6-Dichloro-3-[3-(4-chloro-phenyl)-2,4-dioxo-imid...)
Show SMILES OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1Cn1cc(O)n(-c2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C19H12Cl3N3O4/c20-9-1-3-11(4-2-9)25-15(26)8-24(19(25)29)7-12-16-13(22)5-10(21)6-14(16)23-17(12)18(27)28/h1-6,8,23,26H,7H2,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
120n/an/an/an/an/an/an/an/a



Johannes Gutenberg-Universität

Curated by ChEMBL


Assay Description
Tested for the affinity for the glycine binding site of the N-methyl-D-aspartate glutamate receptor using pig brain membranes in binding assay with [...


J Med Chem 46: 64-73 (2002)


Article DOI: 10.1021/jm020955n
BindingDB Entry DOI: 10.7270/Q2NZ8703
More data for this
Ligand-Target Pair