BDBM50122601 4,6-Dichloro-3-(2-oxo-3-phenyl-imidazolidin-1-ylmethyl)-1H-indole-2-carboxylic acid::CHEMBL351649

SMILES: OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1CN1CCN(C1=O)c1ccccc1

InChI Key: InChIKey=AAUBLVWQSXZMKT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50122601 (4,6-Dichloro-3-(2-oxo-3-phenyl-imidazolidin-1-ylme...) Show SMILES OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1CN1CCN(C1=O)c1ccccc1 Show InChI InChI=1S/C19H15Cl2N3O3/c20-11-8-14(21)16-13(17(18(25)26)22-15(16)9-11)10-23-6-7-24(19(23)27)12-4-2-1-3-5-12/h1-5,8-9,22H,6-7,10H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-Universität Curated by ChEMBL					Assay Description Tested for the affinity for the glycine binding site of the N-methyl-D-aspartate glutamate receptor using pig brain membranes in binding assay with [...				J Med Chem 46: 64-73 (2002) Article DOI: 10.1021/jm020955n BindingDB Entry DOI: 10.7270/Q2NZ8703
					More data for this Ligand-Target Pair