BDBM50122689 2'-(3,3-Dimethyl-2-oxo-piperidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL283610

SMILES: Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CN2CCCC(C)(C)C2=O)-c2ncco2)c1C

InChI Key: InChIKey=FPJPMEXULUCUCB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50122689 (2'-(3,3-Dimethyl-2-oxo-piperidin-1-ylmethyl)-4'-ox...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CN2CCCC(C)(C)C2=O)-c2ncco2)c1C Show InChI InChI=1S/C28H30N4O5S/c1-18-19(2)30-37-25(18)31-38(34,35)24-9-6-5-8-23(24)22-11-10-20(26-29-13-15-36-26)16-21(22)17-32-14-7-12-28(3,4)27(32)33/h5-6,8-11,13,15-16,31H,7,12,14,17H2,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human endothelin A receptor expressed in CHO cells				J Med Chem 46: 125-37 (2002) Article DOI: 10.1021/jm020289q BindingDB Entry DOI: 10.7270/Q2348M3R
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50122689 (2'-(3,3-Dimethyl-2-oxo-piperidin-1-ylmethyl)-4'-ox...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CN2CCCC(C)(C)C2=O)-c2ncco2)c1C Show InChI InChI=1S/C28H30N4O5S/c1-18-19(2)30-37-25(18)31-38(34,35)24-9-6-5-8-23(24)22-11-10-20(26-29-13-15-36-26)16-21(22)17-32-14-7-12-28(3,4)27(32)33/h5-6,8-11,13,15-16,31H,7,12,14,17H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human endothelin B receptor expressed in CHO cells				J Med Chem 46: 125-37 (2002) Article DOI: 10.1021/jm020289q BindingDB Entry DOI: 10.7270/Q2348M3R
					More data for this Ligand-Target Pair