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BDBM50122727 CHEMBL3623132

SMILES: Nc1ncc(C(=O)NC2CNC2)c2ccc(cc12)-c1cccc(F)c1

InChI Key: InChIKey=SNRKPWLLOUSKIH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122727   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase kinase 4


(Homo sapiens (Human))
BDBM50122727
PNG
(CHEMBL3623132)
Show SMILES Nc1ncc(C(=O)NC2CNC2)c2ccc(cc12)-c1cccc(F)c1
Show InChI InChI=1S/C19H17FN4O/c20-13-3-1-2-11(6-13)12-4-5-15-16(7-12)18(21)23-10-17(15)19(25)24-14-8-22-9-14/h1-7,10,14,22H,8-9H2,(H2,21,23)(H,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 401n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of MAP4K4 (unknown origin) by Z'LYTE assay


ACS Med Chem Lett 6: 913-8 (2015)


BindingDB Entry DOI: 10.7270/Q2M32XJB
More data for this
Ligand-Target Pair