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SMILES: CC(C)[C@@H]1N(C)c2ccc(NC(=O)\C=C\C=C\c3ccc(cc3)C(F)(F)F)cc2C[C@@H](CO)NC1=O

InChI Key: InChIKey=WOLVEMPZUIFSII-IHHOKICGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122940   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein kinase C alpha type


(Homo sapiens (Human))		BDBM50122940
PNG
((2S,5S)-(E,E)-8-(5-(4-(trifluoromethyl)phenyl)-2,4...)
Show SMILES CC(C)[C@@H]1N(C)c2ccc(NC(=O)\C=C\C=C\c3ccc(cc3)C(F)(F)F)cc2C[C@@H](CO)NC1=O
Show InChI InChI=1S/C27H30F3N3O3/c1-17(2)25-26(36)32-22(16-34)15-19-14-21(12-13-23(19)33(25)3)31-24(35)7-5-4-6-18-8-10-20(11-9-18)27(28,29)30/h4-14,17,22,25,34H,15-16H2,1-3H3,(H,31,35)(H,32,36)/b6-4+,7-5+/t22-,25-/m0/s1
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Article
PubMed
 12n/an/an/an/an/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Displacement of PDBU from recombinant Protein kinase C alpha with phosphatidylserine

J Med Chem 46: 364-73 (2003)


Article DOI: 10.1021/jm020350r
BindingDB Entry DOI: 10.7270/Q20864P8
More data for this
Ligand-Target Pair