BDBM50122955 2-(4,6-Difluoro-indan-1-ylidene)-acetamide::CHEMBL130217
SMILES: NC(=O)\C=C1/CCc2c1cc(F)cc2F
InChI Key: InChIKey=AQTRJSKRZHDGEX-ZZXKWVIFSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM50122955 (2-(4,6-Difluoro-indan-1-ylidene)-acetamide | CHEMB...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Monoamine oxidase A (MAO-A) | J Med Chem 46: 399-408 (2003) Article DOI: 10.1021/jm020067s BindingDB Entry DOI: 10.7270/Q2VH5N7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysyl oxidase (Homo sapiens (Human)) | BDBM50122955 (2-(4,6-Difluoro-indan-1-ylidene)-acetamide | CHEMB...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against lysyl oxidase | J Med Chem 46: 399-408 (2003) Article DOI: 10.1021/jm020067s BindingDB Entry DOI: 10.7270/Q2VH5N7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50122955 (2-(4,6-Difluoro-indan-1-ylidene)-acetamide | CHEMB...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Monoamine oxidase B (MAO-B) | J Med Chem 46: 399-408 (2003) Article DOI: 10.1021/jm020067s BindingDB Entry DOI: 10.7270/Q2VH5N7F | |||||||||||
More data for this Ligand-Target Pair |