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SMILES: Oc1c2CN(C(c2nc2ccccc12)c1ccc2OCOc2c1)C(=O)c1ccc(Br)o1

InChI Key: InChIKey=YZZBCBSZVRMZDN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122984   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50122984
PNG
(3-Benzo[1,3]dioxol-5-yl-2-(5-bromo-furan-2-carbony...)
Show SMILES Oc1c2CN(C(c2nc2ccccc12)c1ccc2OCOc2c1)C(=O)c1ccc(Br)o1
Show InChI InChI=1S/C23H15BrN2O5/c24-19-8-7-17(31-19)23(28)26-10-14-20(25-15-4-2-1-3-13(15)22(14)27)21(26)12-5-6-16-18(9-12)30-11-29-16/h1-9,21H,10-11H2,(H,25,27)
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MMDB

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Similars
Article
PubMed
 2.10n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development L.L.C.

Curated by ChEMBL


Assay Description
Inhibitory activity against Phosphodiesterase 5 (PDE5) was evaluated

J Med Chem 46: 441-4 (2003)


Article DOI: 10.1021/jm0202573
BindingDB Entry DOI: 10.7270/Q2QR4WHQ
More data for this
Ligand-Target Pair