BDBM50123038 1-(3-Amino-benzo[d]isoxazol-5-yl)-1H-tetrazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL442766

SMILES: Nc1noc2ccc(cc12)-n1nnnc1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key: InChIKey=VZOGQJOJGLRGLO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50123038 (1-(3-Amino-benzo[d]isoxazol-5-yl)-1H-tetrazole-5-c...) Show SMILES Nc1noc2ccc(cc12)-n1nnnc1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C21H16N8O4S/c22-19-16-11-14(9-10-17(16)33-26-19)29-20(25-27-28-29)21(30)24-13-7-5-12(6-8-13)15-3-1-2-4-18(15)34(23,31)32/h1-11H,(H2,22,26)(H,24,30)(H2,23,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of human purified factor Xa				Bioorg Med Chem Lett 13: 369-73 (2003) BindingDB Entry DOI: 10.7270/Q2BG2NC3
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50123038 (1-(3-Amino-benzo[d]isoxazol-5-yl)-1H-tetrazole-5-c...) Show SMILES Nc1noc2ccc(cc12)-n1nnnc1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C21H16N8O4S/c22-19-16-11-14(9-10-17(16)33-26-19)29-20(25-27-28-29)21(30)24-13-7-5-12(6-8-13)15-3-1-2-4-18(15)34(23,31)32/h1-11H,(H2,22,26)(H,24,30)(H2,23,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibitory constant against thrombin using human purified enzymes				Bioorg Med Chem Lett 13: 369-73 (2003) BindingDB Entry DOI: 10.7270/Q2BG2NC3
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50123038 (1-(3-Amino-benzo[d]isoxazol-5-yl)-1H-tetrazole-5-c...) Show SMILES Nc1noc2ccc(cc12)-n1nnnc1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C21H16N8O4S/c22-19-16-11-14(9-10-17(16)33-26-19)29-20(25-27-28-29)21(30)24-13-7-5-12(6-8-13)15-3-1-2-4-18(15)34(23,31)32/h1-11H,(H2,22,26)(H,24,30)(H2,23,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibitory constant against trypsin using human purified enzymes				Bioorg Med Chem Lett 13: 369-73 (2003) BindingDB Entry DOI: 10.7270/Q2BG2NC3
					More data for this Ligand-Target Pair