BDBM50123051 1-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-phenyl]-tetrahydro-pyrimidin-2-one::CHEMBL124844

SMILES: CC(C)c1cc(Oc2c(C)cc(cc2C)N2CCCNC2=O)ccc1O

InChI Key: InChIKey=DMSXJMHCVZWNTG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50123051 (1-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-...) Show SMILES CC(C)c1cc(Oc2c(C)cc(cc2C)N2CCCNC2=O)ccc1O Show InChI InChI=1S/C21H26N2O3/c1-13(2)18-12-17(6-7-19(18)24)26-20-14(3)10-16(11-15(20)4)23-9-5-8-22-21(23)25/h6-7,10-13,24H,5,8-9H2,1-4H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptor				Bioorg Med Chem Lett 13: 379-82 (2003) BindingDB Entry DOI: 10.7270/Q26T0KZB
					More data for this Ligand-Target Pair