BDBM50123281 2-Allyl-6-methoxy-3-thioxo-2,3-dihydro-imidazo[1,5-a]indol-1-one::CHEMBL150870

SMILES: COc1ccc2cc3C(=O)N(CC=C)C(=S)n3c2c1

InChI Key: InChIKey=XRGNLQVAIPKMES-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor receptor R1 (Homo sapiens (Human))	BDBM50123281 (2-Allyl-6-methoxy-3-thioxo-2,3-dihydro-imidazo[1,5...) Show SMILES COc1ccc2cc3C(=O)N(CC=C)C(=S)n3c2c1 Show InChI InChI=1S/C14H12N2O2S/c1-3-6-15-13(17)12-7-9-4-5-10(18-2)8-11(9)16(12)14(15)19/h3-5,7-8H,1,6H2,2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TNF-alpha binding to TNFRc1				Bioorg Med Chem Lett 13: 533-8 (2003) BindingDB Entry DOI: 10.7270/Q2X929N3
					More data for this Ligand-Target Pair