BDBM50123285 2-Ethyl-8-methoxy-6-methoxymethoxy-3-thioxo-2,3-dihydro-imidazo[1,5-a]indol-1-one::CHEMBL151203

SMILES: CCN1C(=O)c2cc3c(OC)cc(OCOC)cc3n2C1=S

InChI Key: InChIKey=GCBWQUPHSUAPLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor receptor R1 (Homo sapiens (Human))	BDBM50123285 (2-Ethyl-8-methoxy-6-methoxymethoxy-3-thioxo-2,3-di...) Show SMILES CCN1C(=O)c2cc3c(OC)cc(OCOC)cc3n2C1=S Show InChI InChI=1S/C15H16N2O4S/c1-4-16-14(18)12-7-10-11(17(12)15(16)22)5-9(21-8-19-2)6-13(10)20-3/h5-7H,4,8H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TNF-alpha binding to TNFRc1				Bioorg Med Chem Lett 13: 533-8 (2003) BindingDB Entry DOI: 10.7270/Q2X929N3
					More data for this Ligand-Target Pair