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SMILES: COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc2CCC(OC(=O)N(C)C)c2c1

InChI Key: InChIKey=OZVCYNCMBGLTRB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123350   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50123350
PNG
(CHEMBL423952 | Dimethyl-carbamic acid 6-(7-methoxy...)
Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc2CCC(OC(=O)N(C)C)c2c1
Show InChI InChI=1S/C25H23N3O5/c1-28(2)25(30)33-22-7-6-14-4-5-15(8-16(14)22)19-10-21(29)17-9-18(24-12-26-13-32-24)23(31-3)11-20(17)27-19/h4-5,8-13,22H,6-7H2,1-3H3,(H,27,29)
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Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II

Bioorg Med Chem Lett 13: 547-51 (2003)


BindingDB Entry DOI: 10.7270/Q2NS0T7H
More data for this
Ligand-Target Pair