BDBM50123411 2'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phenyl}-methanesulfonyl-amino)-methyl]-biphenyl-3-carboxamidine::CHEMBL152344

SMILES: CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccccc1-c1cccc(c1)C(N)=N)S(C)(=O)=O

InChI Key: InChIKey=SAJZWUHSNFZVPD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50123411 (2'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phen...) Show SMILES CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccccc1-c1cccc(c1)C(N)=N)S(C)(=O)=O Show InChI InChI=1S/C28H33N5O3S/c1-20(29)32-16-14-26(15-17-32)36-25-12-10-24(11-13-25)33(37(2,34)35)19-23-6-3-4-9-27(23)21-7-5-8-22(18-21)28(30)31/h3-13,18,26,29H,14-17,19H2,1-2H3,(H3,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of factor II				Bioorg Med Chem Lett 13: 561-6 (2003) BindingDB Entry DOI: 10.7270/Q2DB816X
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50123411 (2'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phen...) Show SMILES CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccccc1-c1cccc(c1)C(N)=N)S(C)(=O)=O Show InChI InChI=1S/C28H33N5O3S/c1-20(29)32-16-14-26(15-17-32)36-25-12-10-24(11-13-25)33(37(2,34)35)19-23-6-3-4-9-27(23)21-7-5-8-22(18-21)28(30)31/h3-13,18,26,29H,14-17,19H2,1-2H3,(H3,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration of the compound to factor Xa				Bioorg Med Chem Lett 13: 561-6 (2003) BindingDB Entry DOI: 10.7270/Q2DB816X
					More data for this Ligand-Target Pair
Trypsin II (Rattus norvegicus)	BDBM50123411 (2'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phen...) Show SMILES CC(=N)N1CCC(CC1)Oc1ccc(cc1)N(Cc1ccccc1-c1cccc(c1)C(N)=N)S(C)(=O)=O Show InChI InChI=1S/C28H33N5O3S/c1-20(29)32-16-14-26(15-17-32)36-25-12-10-24(11-13-25)33(37(2,34)35)19-23-6-3-4-9-27(23)21-7-5-8-22(18-21)28(30)31/h3-13,18,26,29H,14-17,19H2,1-2H3,(H3,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against trypsin				Bioorg Med Chem Lett 13: 561-6 (2003) BindingDB Entry DOI: 10.7270/Q2DB816X
					More data for this Ligand-Target Pair