BDBM50123467 (3-Benzyl-phenyl)-(3-hydroxy-furo[3,2-b]pyridin-2-yl)-methanone::CHEMBL140319
SMILES: Oc1c(oc2cccnc12)C(=O)c1cccc(Cc2ccccc2)c1
InChI Key: InChIKey=BVIXQISADMBONX-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1) | BDBM50123467 ((3-Benzyl-phenyl)-(3-hydroxy-furo[3,2-b]pyridin-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Messina Curated by ChEMBL | Assay Description Strand transfer inhibitory activity against HIV-1 integrase | J Med Chem 48: 7084-8 (2005) Article DOI: 10.1021/jm050549e BindingDB Entry DOI: 10.7270/Q27W6BR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1) | BDBM50123467 ((3-Benzyl-phenyl)-(3-hydroxy-furo[3,2-b]pyridin-2-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integrase | J Med Chem 46: 453-6 (2003) Article DOI: 10.1021/jm025553u BindingDB Entry DOI: 10.7270/Q24T6HRG | |||||||||||
More data for this Ligand-Target Pair |