BDBM50123585 (7-Chloro-quinolin-4-yl)-(3-{4-[3-(4-methoxy-benzylamino)-propyl]-piperazin-1-yl}-propyl)-amine::CHEMBL152286

SMILES: COc1ccc(CNCCCN2CCN(CCCNc3ccnc4cc(Cl)ccc34)CC2)cc1

InChI Key: InChIKey=RTYBEMRAXWNHLF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine-rich protein (Plasmodium falciparum)	BDBM50123585 ((7-Chloro-quinolin-4-yl)-(3-{4-[3-(4-methoxy-benzy...) Show SMILES COc1ccc(CNCCCN2CCN(CCCNc3ccnc4cc(Cl)ccc34)CC2)cc1 Show InChI InChI=1S/C27H36ClN5O/c1-34-24-7-4-22(5-8-24)21-29-11-2-14-32-16-18-33(19-17-32)15-3-12-30-26-10-13-31-27-20-23(28)6-9-25(26)27/h4-10,13,20,29H,2-3,11-12,14-19,21H2,1H3,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61.4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille II Curated by ChEMBL					Assay Description In vitro inhibition of beta-hematin formation				J Med Chem 46: 542-57 (2003) Article DOI: 10.1021/jm020960r BindingDB Entry DOI: 10.7270/Q27W6DDC
					More data for this Ligand-Target Pair