BDBM50123616 CHEMBL3622719
SMILES: C/C(/C=C/C=C(/C)\C=C1/CCCCc2ccccc12)=C\C(O)=O
InChI Key: InChIKey=GVIXTTYIECEGAU-IVVJPBLYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50123616 (CHEMBL3622719) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a |
University of Alabama at Birmingham Curated by ChEMBL | Assay Description Binding affinity to human RXRalpha LBD by fluorescence quenching method | J Med Chem 58: 7763-74 (2015) BindingDB Entry DOI: 10.7270/Q2J38VDC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50123616 (CHEMBL3622719) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
University of Alabama at Birmingham Curated by ChEMBL | Assay Description Agonist activity at human RXRalpha LBD expressed in HEK293 cells transfected with Gal4 reporter assessed as increase of transcription by dual lucifer... | J Med Chem 58: 7763-74 (2015) BindingDB Entry DOI: 10.7270/Q2J38VDC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |