BDBM50123622 6-[3-amino-(3R)-tetrahydro-1H-1-pyrrolyl]-5-fluoro-3-oxo-3H-naphtho[2,1-b]pyrido[3,2,1-kl]phenoxazine-2-carboxylic acid::CHEMBL350251

SMILES: N[C@@H]1CCN(C1)c1c(F)cc2c3c1oc1cc4c(ccc5ccccc45)cc1n3cc(C(O)=O)c2=O

InChI Key: InChIKey=QYQUMHWYIJBNPE-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Taq polymerase 1 (Thermus aquaticus)	BDBM50123622 (6-[3-amino-(3R)-tetrahydro-1H-1-pyrrolyl]-5-fluoro...) Show SMILES N[C@@H]1CCN(C1)c1c(F)cc2c3c1oc1cc4c(ccc5ccccc45)cc1n3cc(C(O)=O)c2=O Show InChI InChI=1S/C28H20FN3O4/c29-21-10-19-24-27(25(21)31-8-7-16(30)12-31)36-23-11-18-15(6-5-14-3-1-2-4-17(14)18)9-22(23)32(24)13-20(26(19)33)28(34)35/h1-6,9-11,13,16H,7-8,12,30H2,(H,34,35)/t16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of Taq DNA polymerase				J Med Chem 46: 571-83 (2003) Article DOI: 10.1021/jm0203377 BindingDB Entry DOI: 10.7270/Q2MS3S4K
					More data for this Ligand-Target Pair