BDBM50123802 5-Chloro-N-(1,4-dimethyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL349595

SMILES: CNc1nc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(C)C1

InChI Key: InChIKey=FDLYNYJLMXYFOP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50123802 (5-Chloro-N-(1,4-dimethyl-[1,4]diazepan-6-yl)-2-met...) Show SMILES CNc1nc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(C)C1 Show InChI InChI=1S/C15H24ClN5O2/c1-17-13-12(16)7-11(15(19-13)23-4)14(22)18-10-8-20(2)5-6-21(3)9-10/h7,10H,5-6,8-9H2,1-4H3,(H,17,19)(H,18,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of the binding of radioligand [3H]spiperone to dopamine receptor D2 in rat brain synaptic membrane				J Med Chem 46: 702-15 (2003) Article DOI: 10.1021/jm020270n BindingDB Entry DOI: 10.7270/Q25H7H06
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50123802 (5-Chloro-N-(1,4-dimethyl-[1,4]diazepan-6-yl)-2-met...) Show SMILES CNc1nc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(C)C1 Show InChI InChI=1S/C15H24ClN5O2/c1-17-13-12(16)7-11(15(19-13)23-4)14(22)18-10-8-20(2)5-6-21(3)9-10/h7,10H,5-6,8-9H2,1-4H3,(H,17,19)(H,18,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...				J Med Chem 46: 702-15 (2003) Article DOI: 10.1021/jm020270n BindingDB Entry DOI: 10.7270/Q25H7H06
					More data for this Ligand-Target Pair