BDBM50123869 (Thiophene-2-carbonyl)-o-tolyl-thiocarbamic acid O-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl] ester::CHEMBL163718

SMILES: Cc1ccccc1N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1

InChI Key: InChIKey=BIKDKLXNQDBIIS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50123869 ((Thiophene-2-carbonyl)-o-tolyl-thiocarbamic acid O...) Show SMILES Cc1ccccc1N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C23H18N2O4S2/c1-15-7-2-5-10-18(15)25(22(28)19-11-6-14-31-19)23(30)29-13-12-24-20(26)16-8-3-4-9-17(16)21(24)27/h2-11,14H,12-13H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair