BDBM50123897 (3-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarbamic acid O-(1-methyl-2-phenoxy-ethyl) ester::CHEMBL166810
SMILES: CC(COc1ccccc1)OC(=S)N(C(=O)c1cccs1)c1cccc(Cl)c1
InChI Key: InChIKey=XZBNTBVEOKRIGA-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50123897 ((3-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a |
Università di Genova Curated by ChEMBL | Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method | J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX | |||||||||||
More data for this Ligand-Target Pair |