BDBM50123912 (4-Nitro-phenyl)-(thiophene-2-carbonyl)-thiocarbamic acid O-(1-methyl-2-phenoxy-ethyl) ester::CHEMBL354267

SMILES: CC(COc1ccccc1)OC(=S)N(C(=O)c1cccs1)c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=LUEBFZCGHIJFKT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50123912 ((4-Nitro-phenyl)-(thiophene-2-carbonyl)-thiocarbam...) Show SMILES CC(COc1ccccc1)OC(=S)N(C(=O)c1cccs1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H18N2O5S2/c1-15(14-27-18-6-3-2-4-7-18)28-21(29)22(20(24)19-8-5-13-30-19)16-9-11-17(12-10-16)23(25)26/h2-13,15H,14H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair