BDBM50124203 5-IODOURACIL::5-Iodo-1H-pyrimidine-2,4-dione::CHEMBL1173

SMILES: Ic1c[nH]c(=O)[nH]c1=O

InChI Key: InChIKey=KSNXJLQDQOIRIP-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydropyrimidine dehydrogenase (Homo sapiens (Human))	BDBM50124203 (5-IODOURACIL | 5-Iodo-1H-pyrimidine-2,4-dione | CH...) Show SMILES Ic1c[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C4H3IN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)				Bioorg Med Chem Lett 13: 867-72 (2003) BindingDB Entry DOI: 10.7270/Q21V5DBW
					More data for this Ligand-Target Pair				3D Structure (crystal)