BindingDB logo
myBDB logout

null

SMILES: CCCNc1ncc(s1)-c1ccncc1-c1cccc(Cl)c1

InChI Key: InChIKey=KUIFETZTZLMNBF-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124357   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
LIM domain kinase 1


(Homo sapiens (Human))		BDBM50124357
PNG
(CHEMBL3622868)
Show SMILES CCCNc1ncc(s1)-c1ccncc1-c1cccc(Cl)c1
Show InChI InChI=1S/C17H16ClN3S/c1-2-7-20-17-21-11-16(22-17)14-6-8-19-10-15(14)12-4-3-5-13(18)9-12/h3-6,8-11H,2,7H2,1H3,(H,20,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 500n/an/an/an/an/an/a



Cancer Research Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrate

J Med Chem 58: 8309-13 (2015)


BindingDB Entry DOI: 10.7270/Q27P917N
More data for this
Ligand-Target Pair