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SMILES: CCCNc1ncc(s1)-c1ccncc1-c1ccc(Cl)cc1

InChI Key: InChIKey=WTINJOMVBPIJBP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124358   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
LIM domain kinase 1


(Homo sapiens (Human))		BDBM50124358
PNG
(CHEMBL3622869)
Show SMILES CCCNc1ncc(s1)-c1ccncc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H16ClN3S/c1-2-8-20-17-21-11-16(22-17)14-7-9-19-10-15(14)12-3-5-13(18)6-4-12/h3-7,9-11H,2,8H2,1H3,(H,20,21)
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Cancer Research Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrate

J Med Chem 58: 8309-13 (2015)


Article DOI: 10.1021/acs.jmedchem.5b01242
BindingDB Entry DOI: 10.7270/Q27P917N
More data for this
Ligand-Target Pair