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BDBM50124359 CHEMBL3622870

SMILES: CCCNc1ncc(s1)-c1ccncc1-c1ccccc1

InChI Key: InChIKey=WXOTWVYCTOWOFC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124359   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LIM domain kinase 1


(Homo sapiens (Human))
BDBM50124359
PNG
(CHEMBL3622870)
Show SMILES CCCNc1ncc(s1)-c1ccncc1-c1ccccc1
Show InChI InChI=1S/C17H17N3S/c1-2-9-19-17-20-12-16(21-17)14-8-10-18-11-15(14)13-6-4-3-5-7-13/h3-8,10-12H,2,9H2,1H3,(H,19,20)
PDB

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PC cid
PC sid
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n/an/a 850n/an/an/an/an/an/a



Cancer Research Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrate


J Med Chem 58: 8309-13 (2015)


BindingDB Entry DOI: 10.7270/Q27P917N
More data for this
Ligand-Target Pair