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BDBM50124403 CHEMBL3623445

SMILES: CCCNc1ncc(s1)-c1cccnc1-c1ccccc1Cl

InChI Key: InChIKey=HTCIIKOJVILAAH-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124403   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LIM domain kinase 1


(Homo sapiens (Human))
BDBM50124403
PNG
(CHEMBL3623445)
Show SMILES CCCNc1ncc(s1)-c1cccnc1-c1ccccc1Cl
Show InChI InChI=1S/C17H16ClN3S/c1-2-9-20-17-21-11-15(22-17)13-7-5-10-19-16(13)12-6-3-4-8-14(12)18/h3-8,10-11H,2,9H2,1H3,(H,20,21)
PDB

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PC cid
PC sid
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n/an/a 327n/an/an/an/an/an/a



Cancer Research Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrate


J Med Chem 58: 8309-13 (2015)


BindingDB Entry DOI: 10.7270/Q27P917N
More data for this
Ligand-Target Pair