BDBM50124404 CHEMBL3623446

SMILES: CCCNc1ncc(s1)-c1cnccc1-c1ccccc1Cl

InChI Key: InChIKey=JCSCZLDSNAYKMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50124404 (CHEMBL3623446) Show SMILES CCCNc1ncc(s1)-c1cnccc1-c1ccccc1Cl Show InChI InChI=1S/C17H16ClN3S/c1-2-8-20-17-21-11-16(22-17)14-10-19-9-7-12(14)13-5-3-4-6-15(13)18/h3-7,9-11H,2,8H2,1H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	574	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrate				J Med Chem 58: 8309-13 (2015) BindingDB Entry DOI: 10.7270/Q27P917N
					More data for this Ligand-Target Pair