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SMILES: COC(=O)c1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key: InChIKey=ATDPSUIIYYUMNQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124592   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50124592
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES COC(=O)c1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23|
Show InChI InChI=1S/C24H25NO3/c1-6-8-18-22-15(11-12-17-20(22)14(2)13-24(3,4)25-17)21-16(23(26)27-5)9-7-10-19(21)28-18/h6-7,9-13,18,25H,1,8H2,2-5H3
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Article
PubMed
 400n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells

J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair